Tocris离子通道调控剂 TOCRIS 4372-10MG,Tocris/2<em>S</em>,6<em>S</em>-Hydroxynorketamine hydrochloride/6095/10/10 mg,其他试剂,其他,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/2<em>S</em>,6<em>S</em>-Hydroxynorketamine hydrochloride/6095/10/10 mg

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Tocris/2S,6S-Hydroxynorketamine hydrochloride/6095/10/10 mg

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Tocris

货号 /

6095/10

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4000-520-616

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Description:DecreasesD-serine(aNMDAco-agoNIST);antidepressant

ChemicalName:(2S,6S)-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanonehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Ketaminemetabolite.DecreasesintracellularD-serine(aNMDAco-agonist)concentrationsinPC-12cells(IC₅₀=0.18nM).Exertsantidepressanteffectsinmice.

LicensingInformation

SoldunderlicensefromtheNIH,USpatent62/313,309

TechnicalData

M.Wt	276.16
Formula	C₁₂H₁₄ClNO₂.HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	1430202-70-2
PubChemID	124201855
InChIKey	ZQJVHBJDLMIKJK-JGAZGGJJSA-N
Smiles	ClC1=C([C@]2(N)C([C@@H](O)CCC2)=O)C=CC=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	27.62	100
	water	13.81	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight276.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.62mL	18.11mL	36.21mL
5mM	0.72mL	3.62mL	7.24mL
10mM	0.36mL	1.81mL	3.62mL
50mM	0.07mL	0.36mL	0.72mL

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