- Overview
- Data/Specifications
- Literature/Support
- How To Use
- Related Products
Overview
Cartilage-link protein (LP) is a glycoprotein present in cartilage that stabilizes the interaction of aggrecan (versican) with hyaluronic acid (HA) in large proteoglycan aggregates.
Related Terms/Symbols:
- Anti-HAPLN1 antibody
- CRTL1
- Hyaluronan and proteoglycan link protein 1
- LP
- Proteoglycan link protein
- Cartilage-linking protein 1
- HAPLN1 gene
- P10915
Data/Specifications
Immunogen: Link Protein from Bovine nasal cartilage
Clone: 8A4
Host: Mouse
Isotype: IgG
Specificity: This antibody recognizes the structurally related amino acid sequence epitopes … PISRP…and ….PITKP that occur in the two proteoglycan tandem repeat motifs of cartilage LP. Thisantibody can be used to detect intact LP 1,2 & 3 as well as a large number of smaller fragmentsthat are generated through proteolytic cleavage during LP catabolism. It recognizesLP in all animal species from chicken to humans.
Purity: Affinity purified
Form: Clear liquid
Concentration: 0.1 mg/mL
Storage: -20° C
Literature/Support
Antibody to Cartilage Link Protein Insert (PDF, 328 KB)
Joint Disease and Aggrecan (blog post)
How To Use
Applications
Western Blot
IHC
RIA
Technical Notes
No enzyme pretreatment required, however chondroitinase and hyaluronidase will increaseantibody sensitivity by exposing epitopes. For WB chondroitinase and hyaluronidase treatmentis recommended.
Related Products
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血液保存液属于医疗器械的几类?
如果需要储液箱,那储液箱和微型定量泵之间用什么连接?是用管道吗?
为了使供输血用的血液能保存一定时间,加入适当的抗凝剂,并尽量防止在保存期发生变质而用的液体。为了防止因糖的消失引起活力降低,尚加入葡萄糖。ACD液(含柠檬酸三钠、柠檬酸、葡萄糖)一般用于血库。添加ACD的血液放在4—6℃条件下保存,可保存三周。另外为防止柠檬酸盐的过量可用加磷酸钠的CPD液。此外还设计了加乳酸钠的ACDL液。如果加入甘油等防冻剂则可长时间冷冻保存红细胞。
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