Product Name | 37,43Gap 27, Connexin MimeticSRPTEKTIFII |
Size | 1 mg |
Catalog # | AS-62642 |
US$ | $79 |
Purity | % Peak Area By HPLC ≥ 95% |
This peptide corresponds to the GAP27 domain of connexin. Connexins, or gap junctions, are a family of structurally-related transmembrane proteins. Gap junctions contain channels that allow the passage of ions and small molecules between adjacent cells. This intercellular communication has been implicated in the coordination of cellular responses to intracellular signaling molecules. Calcium and inositol phosphates are among the second messengers that can pass through gap junction channels. This synthetic connexin-mimetic peptide, Gap 27, was used to evaluate the contribution of gap-junctional communication to osteoclastic bone resorption. It was concluded that gap-junctional communication is necessary for proper bone remodeling. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Berthoud, V. et al. Am. J. Physiol. Lung Cell Mol. Physiol. 279, 619 (2000); Ilvesaro, J. et al. BMC Musculoskel. Disord. 2, 10 (2001); Chaytor, A. et al. Brit. J. Pharmacol. 144, 108 (2005); Boitano, S. and H. Evans Am. J. Physio.l Lung Cell Mol. Physiol. 279, L623 ( 2000). |
Molecular Weight | 1304.6 |
SRPTEKTIFII | |
Sequence(Three-Letter Code) | H - Ser - Arg - Pro - Thr - Glu - Lys - Thr - Ile - Phe - Ile - Ile - OH |
Product Citations | Yi, FX. et al. (2010). Pregnancy Enhances Sustained Ca2+ Bursts and Endothelial Nitric Oxide Synthase Activation in Ovine Uterine Artery Endothelial Cells Through Increased Connexin 43 Function. Biol Reprod 82, 66. |
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各位战友好,因实验要求需要提取人的唾液DNA,但因标本需要在临床采集,无法做到当天就提取DNA,因此天根等漱口水提DNA的试剂盒都不满足实验需求。
之前一直在用艾德莱的唾液DNA保存运输提取试剂盒,但是这段时间下来感觉提取效率太低,而且特别不稳定,经常50%以上的标本都提不出来DNA,或者浓度特别低,完全崩溃的感觉!所以想更换试剂盒或者直接提供唾液DNA的保存液。另国外的这种试剂盒太贵了,因经费问题无法承受,所以希望战友们能够推荐一家效率高些的试剂盒,小女子不胜感激!!
有试剂A和B,传说10-30分钟就可以提取出来。不知道属不属实啊?
而且1000次580块钱!如果有用过的,可否跟我传授一下心得啊?
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