CatalogNumber:RS-0832R-FITC
Quantitysize:0.1ml（dilutewithpH7.40.01MPBSorantibodydiluent）
Background:TheMHCclassIchain-related（MIC）proteinsarerelatedtotheMajorhistocompatibilitycomplex（MHC）classIproteinswhichareubiquitouslyexpressedandmediatetherecognitionofintracellularantigensbycytotoxicTcells.TheMHCclassIchain-related（MIC）proteinsarerecognizedbyNKG2D,areceptoronNKandTcells,andpromoteanti-tumoractivity.MICA,amemberoftheMICfamily,iswidelyexpressedonmanytumors,anditistheMICA/NKG2Dinteractionthatisthoughttostimulatetheanti-tumorreactivitybyTlymphocytes.MICAispresentinvirtuallyeverytissueexceptthenervoussystem,suggestingthatMICproteinexpressionmayonlybeonecomponentoftheanti-tumoractivityoftheimmunesystem.
Function:Seemstohavenoroleinantigenpresentation.Actsasastress-inducedself-antigenthatisrecognizedbygammadeltaT-cells.LigandfortheKLRK1/NKG2Dreceptor.BindingtoKLRK1leadstocelllysis.
MICA/FITC流式抗体说明书Specificity:·anti-MICA/FITCisamousemonoclonalantibodyunconjugated
·specificforMICA/FITCofpig
·useforwesternblotting,ELISA,immunoprecipitationandimmunohistochemistry
·ProteinGaffinitychromatographypurification,purity:>95%
·Isotype:IgG
·molwt:43kDa
Application:·Flow-Cyt=1:50-200
·IF=1:50-200
·Optimalworkingdilutionsmustbedeterminedbytheenduser.
MICA/FITC流式抗体说明书Storage:Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibody,theantibodyisstableforatleasttwoweeksat2-4ºC.
ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.
